XB-IMG-76030
Xenbase Image ID: 76030
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ig. 3. Effects of ADAM13 MO on eye development can be rescued by blocking EfnB sig- naling or by restoring canonical Wnt signaling. One dorsal-animal blastomere of 8-cell stage embryos was injected with the indicated MO (1.5 ng) and, as indicated, with 100 pg mRNA encoding EphB1δC, or full-length (FL) or deleted forms of Xdsh. (A) Embryos were cultured to stage ~ 12.5 and then processed by in situ hybridization for pax6. The injected side is denoted with a red asterisk. (B) Embryos were scored for eye phe- notype at stage ~ 35. **, p b 0.001 in each case; NS, not significant (p = 0.17). See Fig. 1A and Materials and methods for phenotype scoring. Image published in: Wei S et al. (2012) Copyright © 2012. Image reproduced with permission of the Publisher, Elsevier B. V.
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