Xenbase Image ID: 76205

Fig. 2. Ontogeny and hematopoietic potential of the posterior portion of the ventral blood island (pVBI). (A) Ventral blastomere D4 gives rise to the pVBI. (B) At tail bud stages (stage 30, 35hpf) all differentiated myeloid cells (MPO, Elas1, L-plastin) derive from the dorsal marginal zone (DMZ) indicating their anterior hemangioblast origin. At this stage, the ventral marginal zone (VMZ) contains myeloid precursors (SpiB) but no migrating mature myeloid cells. (C) At early larval stages (stage 40, 66hpf), myeloid cells are no longer produced by the DMZ while a second wave differentiating from the VMZ becomes abundant. Image published in: Ciau-Uitz A et al. (2010) Copyright © 2010. Reproduced with permission of the Publisher, University of the Basque Country Press. Gene Synonyms Species Stage(s) Tissue spib.L spi-b, spib-a, spib-b X. laevis Throughout NF stage 29 and 30 myeloid cell hemangioblast anterior ventral blood island mpo.L mpo-A, myeloperoxidase, pmr-1, pmr1, pox2, xpox2 X. laevis Throughout NF stage 29 and 30 anterior ventral blood island myeloid cell hemangioblast mpo.L mpo-A, myeloperoxidase, pmr-1, pmr1, pox2, xpox2 X. laevis Throughout NF stage 40 ventral blood island lcp1.S cp64, l-plastin, lc64p, lpl, pls2 X. laevis Throughout NF stage 29 and 30 post-anal gut myeloid cell Image source: Published Larger Image Printer Friendly View

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