XB-IMG-76438
Xenbase Image ID: 76438
|
Fig. 6. Dlx3 and GATA2 are required cell-autonomously in the non-neural ectoderm for Six1 induction. (A-F′)Host embryos were co-injected with mycGFP mRNA and either Dlx3 MO (A-C′) or GATA2 MO (D-F′) at the two- to eight-blastomere stage and received a neural plate (NP) graft (pigmented) into their belly ectoderm (B-B′) at stage 13. After host embryos reached tailbud stage, grafts are shown in overview (A,D) and at higher magnifications (B-C′,E-F′) in brightfield (B-F), green fluorescent channel (B′-F′) and an overlay (B′-F′). Boxed areas in B and E are shown in detail in C and F, respectively. Six1 induction in non-neural host ectoderm around the graft (asterisks) is specifically suppressed in cells that received high levels of Dlx3 MO or GATA2 MO (arrows or outlined areas of green cells). Image published in: Pieper M et al. (2012) Copyright © 2012. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
Image source: Published Larger Image Printer Friendly View |