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Fig. 8. Model for Nanos1 function in Xenopus PGCs. Xenopus Nanos1 preserves the germline fate through multiple functions: preventing endoderm gene expression by repressing VegT translation, blocking RNA Pol II transcription at MBT, and inhibiting apoptosis. PUM, Pumilio.

Image published in: Lai F et al. (2012)

Copyright © 2012. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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