XB-IMG-76641
Xenbase Image ID: 76641
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Fig. 6. E-cadherin is required for cooperative cellular movement of the non-neural ectoderm layers. (A) Localization of E-cadherin protein in the non-neural ectoderm. E-cadherin is localized not only to the apical junctions (arrows) but also to the border between the superficial and deep cells (arrowheads). White bracket: non-neural ectoderm layer. (B) Trajectories of non-neural cell movements in Ecad-MO-injected embryo. Arrow points towards the dorsal side. (C) Cumulative distance from the tracking data of the Ecad-MO-injected cells. n=3; data are mean±s.e.m. (D) Relative distance between pairs of non-neural superficial and deep cells in Ecad-MO-injected embryos. n=7 pairs. (E,F) Relative aspect ratio and angles of the major axis of the non-neural superficial cells in Ecad-MO-injected embryos. Aspect ratio did not increase as it did in wild type (E), whereas the angles of the major axis were somehow polarized (F). n=9; data are mean±s.e.m. Ecad-MO was injected at 5.3 pmol (44 ng). Scale bars: 20 μm in A; 100 μm in B. Image published in: Morita H et al. (2012) Copyright © 2012. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
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