Xenbase Image ID: 76737

Figure 2. Disruption of neural fold morphogenesis in CRIM1 MO injected embryos. Pigmented embryos showed neural tube morphogenesis defects resulting from CRIM1 MO injection. In (A and B) line intervals mark the distance from the midline to the neural folds to emphasize the defect in morphogenesis that is a result of CRIM1 MO injection. In (A and C) red arrowheads indicate a region of cells that is sloughing from the embryo surface. Image published in: Ponferrada VG et al. (2012) Ponferrada et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Experiment + Assay Source Phenotypes and Disease Xla Wt + crim1 MO + NF42 (whole-mount microscopy) Fig 2 A Anatomical Phenotype abnormal neural tube closure abnormally open neural tube Xla Wt + crim1 MO + NF42 (whole-mount microscopy) Fig 2 C Anatomical Phenotype abnormal cell adhesion Larger Image Printer Friendly View

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