Xenbase Image ID: 76756

Figure 4. Morpholino phenotype. Stage 35 animals developing from embryos injected unilaterally at the two-cell stage with 18 ng of indicated morpholino (MO). Each row shows one embryo in whole-mount in both white light and red morpholino fluorescence and the affected eye in section in transmitted light. For panels in the first two columns, anterior is to the right and dorsal is up. Arrows indicate the location of eye. For the panels in the third column, dorsal is to the right. A–C: Uninjected control animal. D–F:Xenopus MADM-like (xMADML) -MO injected animal. Mild phenotype showing reduced development of ventral retina and poorly differentiated, misorganized fiber cells in the lens. G–I: xMADML-MO injected animal. Severe phenotype showing retina and lens with severely impaired gross morphology. J–L: Control morpholino (CTL-MO) -injected animal exhibiting normal morphology. ce, corneal epithelium; le, lens; nr, neural retina. Scale bar = 400 μm in the first two columns, 100 μm in the third column.Download figure to PowerPoint Image published in: Elkins MB and Henry JJ (2006) Copyright © 2006. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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