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XB-IMG-76846

Xenbase Image ID: 76846


Figure 1. Temporal expression of lung and thyroid markers. Whole mount in situ hybridization was used to compare the temporal expression of key early genes in the development of the thyroid and lung. Expression of nkx2.1 is first detectable in the thyroid (red arrows) at stage 30 and is subsequently expressed in the lung (green arrows) at stage 34. Expression of pax2 begins at stage 32 in the thyroid. Expression of the differentiation markers sftpb and sftpc is first detectable at stage 38.

Image published in: Wang JH et al. (2011)

Image downloaded from an Open Access article in PubMed Central. Copyright ©2011 Wang et al; licensee BioMed Central Ltd.

GeneSynonymsSpeciesStage(s)Tissue
sftpb.LSP-B, xSP-BX.laevisThroughout NF stage 37 and 38 to NF stage 40lung
endoderm
lung primordium
sftpc.SSP-C, xSP-C, SPC, surfcX.laevisThroughout NF stage 37 and 38 to NF stage 40lung
endoderm
nkx2-1.Lttf1, nkx2.1, titf1, Xnkx-2.1, xnkx2-1X.laevisThroughout NF stage 29 and 30 to NF stage 32thyroid
forebrain
telencephalon
olfactory bulb
otic vesicle
head region
neuroectoderm
nkx2-1.Lttf1, nkx2.1, titf1, Xnkx-2.1, xnkx2-1X.laevisSometime during NF stage 33 and 34 to NF stage 40lung
thyroid
endoderm
olfactory bulb
forebrain
telencephalon
head region
otic vesicle
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisThroughout NF stage 29 and 30brain
midbrain-hindbrain boundary
hindbrain
neural tube
posterior neural tube
forebrain
telencephalon
olfactory bulb
pronephric mesenchyme
pharyngeal arch
neuroectoderm
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisThroughout NF stage 32brain
hindbrain
midbrain-hindbrain boundary
neural tube
posterior neural tube
pronephric kidney
pronephric duct
pronephric nephron
neuroectoderm
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisThroughout NF stage 32thyroid
brain
hindbrain
midbrain-hindbrain boundary
neural tube
posterior neural tube
forebrain
telencephalon
olfactory bulb
pronephric kidney
pronephric nephron
pronephric duct
early distal tubule
otic vesicle
head region
pax2.LXPax2, XPax-2, pax-2, pax2-a, pax2-bX.laevisThroughout NF stage 33 and 34 to NF stage 40thyroid
endoderm
brain
midbrain-hindbrain boundary
hindbrain
neural tube
posterior neural tube
pronephric kidney
pronephric nephron
pronephric duct
early distal tubule
forebrain
telencephalon
hypothalamus

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