Xenbase Image ID: 76892

Figure 1. Xenopus mandibular trigeminal nerve innervates the cement gland. (A) Whole mount immunostaining of a Xenopus embryo (St. 29) labeled with β-tubulin antibody and cleared in Murray's clearing solution reveals the embryonic axonal network, including the prominent mandibular trigeminal nerve. (B) The mandibular trigeminal nerve (arrow) extends between the eye vesicle (e) and otic vesicle (ov), and then turns ventrally before terminating at the ventral region of the cement gland (asterisk). Deletion of cement glands results in the loss of trigeminal targeting, where the axons either (C) stop growth, or extended (D) dorsally or (E) ventrally. Because the embryos are transparent, trigeminal axons on the opposite side could also be detected. In the cement gland null embryos, trigeminal axons on either side of the face do not necessarily project erroneously in the same directions. Image published in: Huang JK et al. (2007) Copyright © 2007 Huang et al; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue tubb2b.S N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 29 and 30 brain trigeminal nerve spinal cord forebrain telencephalon diencephalon cranial nerve optic nerve abducens nerve glossopharyngeal nerve vagus nerve midbrain Image source: Published Larger Image Printer Friendly View

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