XB-IMG-76913
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Additional file 4. High doses of GATA5 MOs reduce gastrula-stage Hex expression. G5 and G5SP MO cause downregulation of Hex expression in gastrulae (st. 11) only at high doses (20 ng for G5 (30/37 embryos) and 44 ng for G5SP (27/33 embryos), whereas 50 ng of C1 MO has no effect (15/17 embryos with normal expression). G5 MOs cause gastrulation defects which cause a delay in blastpore closure and the shape of Hex domain of expression. Blastopore is highlighted by dashed line. Image published in: Haworth KE et al. (2008) Copyright © 2008 Haworth et al; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license
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