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XB-IMG-76963

Xenbase Image ID: 76963

Figure 6. Expression of selected transdifferentiation genes during development. In situ hybridisation of five regeneration associated genes (RAG). Dark blue staining marks expression, and a white arrow indicates the position of the lens. A) Nipsnap1 expression appears in lens cells at stage 30 (A) and is also found in the pronephros (pn) and branchial arches (ba) from stage 32 (B). At stage 36, Nipsnap1 expression is seen in the pronephros and pronephritic duct (pnd) and otic vesicle (ov) as well as in the periphery of the lens (C). D) Tbp1b is expressed predominantly in lens, otic vesicle and branchial arches at stage 32. E) Tcf7 is expressed in lens and choroid fissure of the retina (cf), the midbrain-hindbrain junction (m/h), cement gland (cg), otic vesicle and pronephritic duct at at stage 32. F) Pdik1l is expressed in the developing lens and retina (re) and branchial arches at stage 32. G) Dvl2 is expressed in eye tissues but is not specific, with expression extending throughout the embryo including the somites (s), otic vesicle and branchial arches. Embryos are oriented with anterior to the left and dorsal uppermost.

Image published in: Day RC and Beck CW (2011)

Copyright ©2011 Day and Beck; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

GeneSynonymsSpeciesStage(s)Tissue
nipsnap1.LX. laevisThroughout NF stage 29 and 30lens
retina
mesoderm
nipsnap1.LX. laevisThroughout NF stage 32lens
pronephric kidney
eye
retina
lateral plate mesoderm
pronephric duct
pharyngeal arch
nipsnap1.LX. laevisThroughout NF stage 35 and 36lens
otic vesicle
pronephric kidney
pronephric duct
eye
retina
pharyngeal region
taf1b.LX. laevisThroughout NF stage 32lens
otic vesicle
somite
olfactory placode
head
pharyngeal arch
tcf7.Stcf-1, tcf1, Xtcf-1, Xtcf1X. laevisThroughout NF stage 32lens
retina
otic vesicle
cement gland
choroid fissure
midbrain-hindbrain boundary
pronephric duct
eye
pdik1l.Spdik1l-a, pdik1l-bX. laevisThroughout NF stage 32eye
lens
retina
pharyngeal arch
dvl2.Ldishevelled, dsh, dvl, LOC108703580, Xdsh, Xdsh2, xDvl2X. laevisThroughout NF stage 32eye
otic vesicle
somite
head
pharyngeal arch

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