Xenbase Image ID: 76975

Fig. 2. Fgf is required for the patterning of late LPM markers. Hand1 (A and B) and foxf1 (C and D) are normally restricted in the anterior and middle LPM with a clear domain free of expression in both cases. When embryos are treated with SU5402, both hand1 (B) and foxf1 (D) are expressed along the entire anterior–posterior axis. Conversely, the LPM expression domains of both hoxc10 (E and F; normally expressed in the posterior half of the LPM) and tnni3 (G and H; marker of cardiac differentiation) are completely undetectable when Fgf signalling is inhibited. (A–F): lateral view of the embryos is shown, with anterior toward the left, dorsal at top. (G–H); ventral view of the heart region is shown, with anterior toward left. The total number of embryos examined for each panel is indicated in the lower left hand corner. Image published in: Deimling SJ and Drysdale TA (2011) Copyright © 2011. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hand1.L eHand, hand-1 X. laevis Throughout NF stage 28 to NF stage 29 and 30 lateral plate mesoderm anterior ventral blood island blood vessel vascular plexus foxf1.L acdmpv, fkhl5, foxf1-a, foxf1-b, freac1, xfd-13 X. laevis Throughout NF stage 28 to NF stage 29 and 30 lateral plate mesoderm olfactory region pharyngeal arch anterior dorsal lateral plate region hoxc10.L LOC108709895, MGC80182, XHoxc10 X. laevis Throughout NF stage 28 to NF stage 29 and 30 somite tail bud lateral plate mesoderm presomitic mesoderm tail tip posterior tnni3.L c-troponin, cardiac tropin T, cardiac troponin I, cTnI, ctnIc, cTNT, TIc, TnIc, tnnic, troponin-ic, XcTnI, XTnIc X. laevis Throughout NF stage 28 to NF stage 29 and 30 cardiac mesoderm heart primary heart field secondary heart field Image source: Published Larger Image Printer Friendly View

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