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XB-IMG-77159

Xenbase Image ID: 77159


Fig. 5. Liver and ventral pancreas defects in hhex morphants. Probes or methods for whole mount staining are indicated on the left. (A and B) Bisected embryos, dorsal toward top. (C) Lateral view, head toward the left. (I and J) Bisected embryos, anterior toward the left. (K) Lateral view, head toward the left. The white arrowhead (N) indicates the missing expression of fibrinogen in the liver anlage. (S) Bisected embryos, anterior toward the left. Phenotype is as follows: B, 19/20; D, 20/22; F, 24/25; H, 34/41; J, 25/27; L, 38/44; N, 19/20; P, 36/42; R, 16/72 (for detailed phenotype analysis, see Fig. S7); T, 22/23; V, 41/41. (W) Statistical analysis of phospho-histone H3-positive cells in the outlined areas in U and V. Thirty-four samples from 17 bisected embryos were counted from either control MO or hhex MO-injected embryos. P value (0.309) was determined by the paired, two-tailed t test.

Image published in: Zhao H et al. (2012)

Copyright © 2012. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneSynonymsSpeciesStage(s)Tissue
hhex.Lhex, tHex, XHexX. laevisThroughout NF stage 13endoderm
dorsal
anterior
hhex.Lhex, tHex, XHexX. laevisThroughout NF stage 24endoderm
foregut
liver primordium
hhex.Lhex, tHex, XHexX. laevisThroughout NF stage 32pancreas
endoderm
liver
foregut
alimentary system
hhex.Lhex, tHex, XHexX. laevisThroughout NF stage 42pancreas
liver
foregut
alimentary system
foxa2.LHNF-3B, hnf3-beta, hnf3b, hnf3beta, LOC108717763X. laevisThroughout NF stage 18anterior
ventral
endoderm
anterior neural fold
nr1h5.Lfor1X. laevisThroughout NF stage 37 and 38endoderm
liver
foregut
alimentary system
pdx1.Sipf1, pdx-1, STF-1, XlHbox-8, XlHbox8X. laevisThroughout NF stage 37 and 38pancreas
endoderm
foregut
alimentary system
stomach
duodenum
dorsal pancreatic bud
ptf1a.Sptf1a-a, ptf1a-b, Ptf1a/p48, XPtf1aX. laevisThroughout NF stage 37 and 38pancreas
eye
hindbrain
ventral
fga.Sfibrinogen, Fibrinogen, A alpha polypeptideX. laevisThroughout NF stage 37 and 38endoderm
tail
foregut
midgut
hindgut
alimentary system

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