Xenbase Image ID: 77226

Figure S6. Gsc-depleted embryos. In situ hybridization of bisected hhex:gfp transgenic embryos injected with Gsc-MO (40 ng). At stage 10.5 Gsc-MO embryos exhibit increased wnt8, vent1, and vent2, mRNA levels, but hhex expression is unchanged. By stage 12.5 Gsc-MO embryos fail to maintain hhex expression. Image published in: Rankin SA et al. (2011) Copyright © 2011. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hhex.L hex, tHex, XHex X. laevis Throughout NF stage 10.5 endoderm endomesoderm dorsal wnt8a.L wnt-8, wnt8, Xwnt-8, Xwnt8 X. laevis Throughout NF stage 10.5 involuted ventral mesoderm mesoderm ventx1.2.S vent-1, vent1, Xvent-1, Xvent1 X. laevis Throughout NF stage 10.5 involuting marginal zone involuted ventral mesoderm ventral ventx2.2.L vent-2, vent2, Xom, xvent-2, xvent2 X. laevis Throughout NF stage 10.5 involuted ventral mesoderm involuting marginal zone mesoderm ventral hhex.L hex, tHex, XHex X. laevis Throughout NF stage 12 involuted dorsal mesoderm Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + gsc MO + NF10.5 (in situ hybridization) fig.S6 Expression Phenotype increased amount ventx1.2.L expression in endoderm mislocalised ventx1.2.L expression in endoderm increased amount ventx2.2.L expression in endoderm mislocalised ventx2.2.L expression in endoderm increased amount wnt8a.L expression in dorsal endomesoderm mislocalised wnt8a.L expression in dorsal endomesoderm Xla Wt + gsc MO + NF12 (in situ hybridization) fig.S6 Expression Phenotype decreased amount hhex.L expression in involuted dorsal mesoderm Larger Image Printer Friendly View

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