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Figure S7. Otx2- and Lim1-depleted embryos. In situ hybridization of bisected gastrula embryos injected with Otx2-MO and/or Lim1-MOs (20 ng each). Image published in: Rankin SA et al. (2011) Copyright © 2011. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hhex.L hex, tHex, XHex X. laevis Throughout NF stage 10.5 endomesoderm mesoderm involuted dorsal mesoderm gsc.L goosecoid, gsc-a, gsc-b, Xgsc X. laevis Throughout NF stage 10.5 involuted dorsal mesoderm prechordal plate chrd.S chd, chordin, chrd.1, LOC108716939, X-chordin X. laevis Throughout NF stage 10.5 endomesoderm involuted dorsal mesoderm mesoderm axial mesoderm ventx1.2.S vent-1, vent1, Xvent-1, Xvent1 X. laevis Throughout NF stage 10.5 ventral mesoderm involuted ventral mesoderm ventx2.2.L vent-2, vent2, Xom, xvent-2, xvent2 X. laevis Throughout NF stage 10.5 ventral mesoderm involuted ventral mesoderm Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + lhx1 MO + NF10.5 (in situ hybridization) fig.S7 Expression Phenotype decreased amount chrd.1.L expression in involuted dorsal mesoderm decreased amount gsc.L expression in involuted dorsal mesoderm decreased amount hhex.L expression in dorsal endomesoderm Xla Wt + lhx1 MO + otx2 MO + NF10.5 (in situ hybridization) fig.S7 Expression Phenotype increased amount chrd.1.L expression in involuted dorsal mesoderm decreased amount chrd.1.L expression in involuted dorsal mesoderm mislocalised chrd.1.L expression in involuted dorsal mesoderm decreased amount gsc.L expression in involuted dorsal mesoderm decreased amount hhex.L expression in dorsal endomesoderm Xla Wt + otx2 MO + NF10.5 (in situ hybridization) fig.S7 Expression Phenotype increased amount chrd.1.L expression in involuted dorsal mesoderm decreased amount chrd.1.L expression in involuted dorsal mesoderm mislocalised chrd.1.L expression in involuted dorsal mesoderm decreased amount gsc.L expression in involuted dorsal mesoderm decreased amount hhex.L expression in dorsal endomesoderm Larger Image Printer Friendly View

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