Xenbase Image ID: 77239

Figure 3. xPAPC depletion does not affect patterning and innervation events. xPAPC antisense morpholinos were single side injected to examine possible effects in patterning (A, A', B, B') or innervation (C, C', D, D'). (A, A', B, B') ISH at stage 26 for the anterior otic marker Nkx5.1, n = 15 (A, A') and the ventral marker Pax2, n = 31 (B, B'). xPAPC depletion shows no impact. (C, C', D, D') ISH for NeuroD at stage 26, n = 21 (C, C', C'') and stage 28, n = 8 (D, D', D''). NeuroD expression is unaffected from xPAPC knockdown. Black dot marks the otic vesicle. epIX, epVII = epibranchial placodes; gVIII = statoacoustic ganglion; gPr = profundal placode; pAD = anterodorsal lateral line placode; pM = middle lateral line placode. Scale bar 500 μm (A-C', D-D'), 100 μm (C'', D''). Image published in: Jung B et al. (2011) Copyright ©2011 Jung et al; licensee BioMed Central Ltd. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue hmx3.L nkx-5.1, nkx5-1, nkx5.1 X. laevis Throughout NF stage 26 otic placode anterior pax2.L LOC108697493, pax-2, pax2-a, pax2-b, XPax-2, XPax2 X. laevis Throughout NF stage 26 otic placode midbrain-hindbrain boundary optic vesicle neurod1.L neurod, neuroD, neurod1-a, neurod1-b, XNeuroD X. laevis Throughout NF stage 26 profundal placode trigeminal placode lateral line placode optic vesicle neurod1.L neurod, neuroD, neurod1-a, neurod1-b, XNeuroD X. laevis Throughout NF stage 28 profundal placode trigeminal placode facial nerve glossopharyngeal nerve epibranchial placode facial epibranchial placode glossopharyngeal epibranchial placode trunk placode Image source: Published Larger Image Printer Friendly View

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