XB-IMG-77250
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Fig. 6. xCOUP-TF-B enhanced transcription of both xCyp26A and xCyp26C. (A) RT-PCR was performed with stage-13 embryos injected with 50 pg (lane 2) or 100 pg (lane 3) of xCOUP-TF-B. We observed gene expression of Cyp26A (column 1), Cyp26C (column 2), XBF-1 telencephalon marker: column 3), Xotx2 (forebrain marker: column 4), xSlug (neural crest marker: column 5), and ODC (quantitative control: column 6). (B,C) Whole mount in situ hybridization of embryos injected with 75 pg of xCOUP-TF-B with xCyp26A (B,B or xCyp26C (C,C.The injection side was marked with Red-Gal. (D) Schematic model of xCOUP-TF function. Image published in: Tanibe M et al. (2012) Copyright © 2012. Reproduced with permission of the Publisher, University of the Basque Country Press.
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