Xenbase Image ID: 77262

Fig. 3 (Right). Terminal mitosis in the inner ear of stage 47 X. laevis that were transiently exposed to BrdU at stages 37 (A), 42 (B) and 45 (C). Anterior to posterior sections representing the entire inner ear show the presence of BrdU-positive cells (black/dark-grey) with birthdates from earlier stages (S37, A1-A3; S42, B1-B3; S45, C1-C3) in stage 47 otic epithelia. Cells that had undergone terminal mitosis (arrows, dashed circles) are predominantly seen in the central regions of the emerging sensory epithelia of the utricle (A1, B1, C1) and of the sacculus (A2-A3, B2-B3, C2-C3) regardless of stage of BrdU exposure. Images of the saccular region within the dashed circles are shown at higher magnification underneath the corresponding panels. Control sections processed for immunohistochemistry with secondary antibody but without primary (anti-BrdU) antibody and counterstained with hematoxylin are shown in panels (A4, B4, C4) for the saccular epithelium. Hematoxylin counterstain (light grey). Scale bar, 50 μm. Image published in: Quick QA and Serrano EE (2007) Copyright © 2007. Reproduced with permission of the Publisher, University of the Basque Country Press. Larger Image Printer Friendly View

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