Xenbase Image ID: 77263

Fig. 4 (Left). Comparison of new cell production (A) and terminal mitosis (B) in the saccular region of the X. laevis inner ear. (A) Cell proliferation observed after three hours of development following transient BrdU exposure at stages 37 (A1), 42 (A2) and 45 (A3). BrdU-positive cells (red/brown) flank the emerging saccular epithelium (dashed circles) at all stages. Few BrdU-positive cells are detected within the thickened region of the saccular epithelium. (B) Terminal mitosis observed at stage 47 following BrdU exposure at stage 37 (B1), 42 (B2) and 45 (B3). Images of the saccular region within the dashed circles are shown at higher magnification underneath the corresponding panels. In contrast to Fig. 4A, BrdU-positive cells (black/ dark-grey) with birthdates from earlier stages are prevalent in the thickened central region of the saccular epithelium (dashed circle). Hematoxylin counterstain (A, blue/violet; B, light grey). Scale bar, 50 μm. Image published in: Quick QA and Serrano EE (2007) Copyright © 2007. Reproduced with permission of the Publisher, University of the Basque Country Press. Larger Image Printer Friendly View

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