Xenbase Image ID: 77342

Figure 3. miR-24a knockdown has no effect on proliferation, but leads to an increase in apoptosis. (A) Immunohistochemistry for phosphorylated histone3 (PH3, in red) shows that there is no significant difference in proliferation between control eyes and 24aMO-injected eyes (n = 6 embryos per stage; 18 sections per embryo; sections are 12 μm; error bars are SEM). (B) Knockdown of miR-24a results in a significant increase in apoptosis at all stages assayed, measured by the number of TUNEL-positive nuclei per 20 (n = 6 embryos per stage; 11 sections per embryo; error bars are SEM). Image published in: Walker JC and Harland RM (2009) Copyright © 2009. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article. Larger Image Printer Friendly View

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