Xenbase Image ID: 77770

Fig. 3. Early neural genes were down-regulated by inhibition of XSIP1 mRNA translation, while mesodermal genes were not influenced. Whole-mount in situ hybridization analysis of Xbra (A,E) and chordin (B,F) expression in stage 11 embryos, which had been injected with either control MO or XSIP1 MO into the dorsal marginal zone of the four-cell-stage embryo. An equivalent analysis of SoxD (C,G) and Zic3 (D,H) expression in stage 11 embryos, although one dorsal-animal blastomere of the eight-cell-stage embryo was injected in these embryos. SoxD and Zic3 expression were down-regulated in the XSIP1 MO-injected area (G,H; arrowhead), while they overlapped in the control MO-injected area (C,D). The dorsal view of all embryos is shown. Image published in: Nitta KR et al. (2004) Copyright © 2004. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue tbxt.S bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 11 marginal zone chrd.S chd, chordin, chrd.1, LOC108716939, X-chordin X. laevis Throughout NF stage 11 involuted dorsal mesoderm axial mesoderm upper blastopore lip sox15.L sox-d, sox20, sox26, sox27, soxd, xsoxd X. laevis Throughout NF stage 11 animal cap zic3.S xzic3, Zinc finger protein of the cerebellum 3 X. laevis Throughout NF stage 11 neuroectoderm dorsal involuted dorsal mesoderm Image source: Published Larger Image Printer Friendly View

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