Xenbase Image ID: 77826

Fig. 3. Repression of Xbra results in a repression of Hox genes. Nonorganiser site injection of factors that lead to a repression of Xbra. (A–F) Vegetal views (organiser is up) of noninjected (ni) control embryo (A) and embryos injected with otx-2 (B), mix.1 (C), gsc (D), Sia (E) and Xbra-EnR (F) mRNAs. All injected embryos show downregulation of Hoxd-1 on the site of injection (arrowheads). (G–L) Non-organiser side views of noninjected embryos (G, I, K) and Xbra-EnR-injected embryos (H, J, L). Staining for Hoxb-4 (G, H), Hoxc-6 (I, J) and Hoxb-9 (K, L) show that these Hox genes are also downregulated by repression of Xbra function. Arrowheads point to the side of injection. Image published in: Wacker SA et al. (2004) Copyright © 2004. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hoxd1.S MGC131028, Xhox.lab, xhox.lab1, xhoxd1, xlab, Xlab-1 X. laevis Throughout NF stage 11 mesoderm involuted dorsal mesoderm marginal zone ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone hoxb4.S LOC494794, XHox-1a, XHox-b4, xHox1a X. laevis Throughout NF stage 11 mesoderm marginal zone hoxc6.S ACI, xeb1, XlHbox1 X. laevis Throughout NF stage 11 ectoderm mesoderm marginal zone hoxc9-like.L X. laevis Throughout NF stage 11 marginal zone Image source: Published Larger Image Printer Friendly View

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