Xenbase Image ID: 77828

Fig. 5. Ectopic activation of the BMP pathway expands Hox expression to the organiser side. (A–H) Vegetal views (organiser is up) of noninjected (ni) and Alk-6-injected embryos stained for Hoxd-1 (A, B), Hoxc-6 (C, D), Hoxa-7 (E, F) and Hoxb-8 (G, H). Ectopic Alk-6 expression results in an expansion of the Hox expression on the organiser side. (I) A cross section (as indicated in the schematic drawing) of the marginal zone of an Alk-6-injected embryo (stage 11.5, organiser side indicated by O). Ectopic expression of Hoxd-1 on the organiser side is present in the mesoderm, but not in the overlying ectoderm (arrowheads). The dashed lines indicate Brachet’s cleft, which separates involuted mesoderm and the non-involuted tissue (i.e. neuroectoderm on the organiser side and preinvoluted mesoderm on the non-organiser side). Image published in: Wacker SA et al. (2004) Copyright © 2004. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hoxd1.S MGC131028, Xhox.lab, xhox.lab1, xhoxd1, xlab, Xlab-1 X. laevis Throughout NF stage 11 mesoderm involuted dorsal mesoderm marginal zone ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone involuted ventral mesoderm hoxc6.S ACI, xeb1, XlHbox1 X. laevis Throughout NF stage 12 ectoderm mesoderm ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone hoxa7.L antp, Hox-A7, hox36, Xhox-36, xlhbox 3, XlHbox-3, XlHbox5 X. laevis Throughout NF stage 12 mesoderm ventral marginal zone ventro-lateral marginal zone hoxb8.L Hox 2.4, hoxb-8, LOC108700806, LOC108702520 X. laevis Throughout NF stage 12.5 posterior ventro-lateral marginal zone dorso-lateral marginal zone Image source: Published Larger Image Printer Friendly View

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