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Fig. 6. Geminin suppression of mesoderm and endoderm depends on Polycomb but is independent of Oct25/60 and Sox2 activities. Geminin RNA (120 pg) with or without 8 ng of MOs (16 ng Oct60MO) + 30 pg β-galactosidase RNA was injected into one cell of eight-cell embryos, with in situ hybridization at stage 11.5. Red-gal staining and white or red arrowheads mark injected regions. Below are additive results for four experiments shown as fractions of embryos with indicated effects (embryo numbers analyzed are in parentheses). Image published in: Lim JW et al. (2011) Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue tbxt.S bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury X. laevis Throughout NF stage 11.5 blastopore lip involuting marginal zone post.L LOC108704914, Xpo X. laevis Throughout NF stage 11.5 marginal zone ventro-lateral marginal zone dorso-lateral marginal zone dorsal marginal zone blastopore lip sox17a.L sox17 alpha, sox17-alpha, Sox17alpha, tSox17alpha, xsox17, Xsox17-alpha, xsox17a, Xsox17alpha, xSox17alpha1, xSox17alpha2 X. laevis Throughout NF stage 11.5 ventro-lateral marginal zone dorso-lateral marginal zone dorsal marginal zone upper blastopore lip Image source: Published Larger Image Printer Friendly View

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