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XB-IMG-77880

Xenbase Image ID: 77880


Fig. 3. Osr1/Osr2 are required for wnt2b and raldh2 expression in the lpm. (A-X) Analysis of stage 34/35 unilateral-injected embryos shows that Osr1/Osr2 are required for expression of nkx2.1 (A-C) and sox2 (D-F) in the epithelium, whereas shh (G-I) is unaffected. In the lpm, wnt2b (J-L) and raldh2 (M-O) are absent, while foxf1 is unaffected (P-R). Black arrows indicate normal expression on the control side and red arrows indicate lack of expression on the Osr1/Osr2-MO-injected side (right). Endoderm outlined by a yellow line. Numbers of embryos with the shown phenotype are indicated. fg, foregut; hg, hindgut; de, dorsal endoderm; pe, posterior endoderm; e, esophagus; l/t, presumptive lung and trachea; lv, liver; lpm, lateral plate mesoderm; k, kidney; s, stomach.

Image published in: Rankin SA et al. (2012)

Copyright © 2012. Image reproduced on Xenbase with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

GeneCloneSynonymsSpeciesStage(s)Tissue
nkx2-1.L ttf1, nkx2.1, titf1, Xnkx-2.1, xnkx2-1X.laevisSometime during NF stage 33 and 34 to NF stage 35 and 36lung
endoderm
brain
forebrain
eye
lung primordium
trachea
foregut
thyroid primordium
sox2.S XLSOX-2, Sox-2, XSox2, Xsox-2, anop3, mcops3X.laevisSometime during NF stage 33 and 34 to NF stage 35 and 36stomach
brain
spinal cord
foregut
endoderm
head
pharyngeal arch
otic vesicle
esophagus
eye
shh.L hedgehog, Xhh, sonic hedgehog, X-SHH, xshh, vhh-1X.laevisSometime during NF stage 33 and 34 to NF stage 35 and 36endoderm
trachea
esophagus
foregut
gall bladder primordium
pharyngeal arch
mandibular arch
hyoid arch
branchial arch
head
wnt2b.L Xwnt-2b, xwnt2b, wnt-2b, wnt2b-a, wnt2b-bX.laevisSometime during NF stage 33 and 34 to NF stage 35 and 36lateral plate mesoderm
lens placode
otic vesicle
pineal gland
pharyngeal arch
aldh1a2.L raldh2, XRaldh2, raldh-2X.laevisSometime during NF stage 33 and 34 to NF stage 35 and 36lateral plate mesoderm
brain
lens
otic vesicle
periocular region
pronephric kidney
pronephric duct
adenohypophyseal placode
midbrain
hindbrain
foxf1.L xfd-13, fkhl5, acdmpv, freac1, foxf1-a, foxf1-bX.laevisSometime during NF stage 33 and 34 to NF stage 35 and 36lateral plate mesoderm
pharyngeal arch
anterior dorsal lateral plate region
olfactory region
head region

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