Xenbase Image ID: 78277

FIG. 1. Juxtaposition of the notochord and dorsal endoderm tissues in mouse, chick, and frog embryos. In all cases, the notochord (arrow) contacts the dorsal endoderm (arrowheads). The positions of the neural tube (nt) and somites (s) are indicated. (A) Transverse section through the foregut of a stage 34 frog embryo. (B) Transverse section through the hindgut of a HH stage 12 chick embryo. (C) Transverse section through the foregut of an E8.5 mouse embryo. (D) Diagram showing dorsolateral signaling from the notochord to the neural tube and somites (red) and ventral signaling to the endoderm (yellow). Note the marked difference in the size of the notochord relative to surrounding tissues in these three organisms. Image published in: Cleaver O and Krieg PA (2001) Copyright © 2001. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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