Xenbase Image ID: 78642

Fig. 1. XMeis3 and RA cooperatively regulate HoxD1 expression. Two-cell albino embryos were injected unilaterally into the animal hemisphere of one blastomere. All embryos are injected on the right side, viewed dorsally, and are oriented anterior (top), posterior (bottom). (A) Control (uninjected). (B) 0.8 ng XMeis3 RNA, HoxD1 expression is increased in 67% of the embryos (n = 30/45). (C) 7.5 ng of XMeis3 MO; 50 pg h-gal RNA, HoxD1 expression is reduced in 52% of the embryos (n = 11/21). (D) 0.1 AM RA (uninjected), HoxD1 expression is anteriorly expanded in 98% of the embryos (n = 61/62). (E) 0.8 ng XMeis3 RNA; 0.1 AM RA, HoxD1 expression is highly increased in 71% of the embryos (n = 27/38). (F) 7.5 ng XMeis3 MO; 0.1 AM RA, HoxD1 expression is reduced in 66% of the embryos (n = 21/32). (G) 0.8 ng XCYP26 RNA; 50 pg h-gal RNA, HoxD1 expression is reduced in 70% of the embryos (n = 16/23). (H) 0.8 ng XCYP26 RNA; 0.8 ng XMeis3 RNA; 50 pg h-gal RNA, HoxD1 expression is reduced in 90% of the embryos (n = 18/20). Image published in: Dibner C et al. (2004) Copyright © 2004. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hoxd1.S MGC131028, Xhox.lab, xhox.lab1, xhoxd1, xlab, Xlab-1 X. laevis Throughout NF stage 11.5 dorsal neuroectoderm Image source: Published Larger Image Printer Friendly View

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