Xenbase Image ID: 78644

Fig. 3. RA modulates XMeis3 activation of Krox20 expression. Two-cell albino embryos were injected unilaterally into the animal hemisphere of one blastomere. All embryos are injected on the right side, viewed dorsally, and are oriented anterior (top), posterior (bottom). (A) Control (uninjected). (B) 0.8 ng XMeis3 RNA, Krox20 expression is increased in 70% of the embryos (n = 62/89). (C) 7.5 ng of XMeis3 MO, Krox20 expression is decreased in 68% of the embryos (n = 32/47). (D) 0.1 AM RA (uninjected), Krox20 expression stripes are fused in 98% of the embryos (81/83). (E) 0.8 ng XMeis3 RNA; 0.1 AM RA, ectopic Krox20 expression is decreased in 78% of the embryos (n = 62/80). (F) 7.5 ng XMeis3 MO; 0.1 AM RA; 50 pg h-gal RNA, Krox20 expression is decreased in 89% of the embryos (n = 49/55). (G) 0.8 ng XCYP26 RNA, Krox20 expression is posteriorized in 89% of the embryos (17/19). (H) 0.8 ng XCYP26 RNA; 0.8 ng XMeis3 RNA, Krox20 expression is highly expressed in 68% of the embryos (13/19). Image published in: Dibner C et al. (2004) Copyright © 2004. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue egr2.L EGR-2, Krox-20, krox20, XKr20, XKrox-20 X. laevis Throughout NF stage 20 hindbrain rhombomere rhombomere R3 rhombomere R5 Image source: Published Larger Image Printer Friendly View

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