Xenbase Image ID: 79137

Fig. 2. Inhibition of xBic-C leads to edema formation. (A) Sequence of the two pseudoalleles of Xenopus Bicaudal-C. The positions of the two antisense morpholino oligomers are indicated. (B) In vitro transcription/translation of xBic-C in the presence or absence of xBic-C-MO1. Lane 1, pCSII; lane 2 and 3, xBic-C-HA-pCSII; lane 4 and 5, xBic-C*-HA-pCSII. (C, D) Morphology of uninjected and xBic-C-MO1 + 2-injected embryo displaying large edema. (E) Quantification of edema formation at stage 43 of uninjected control embryos and Xenopus embryos injected radially at the 2–4 cell stage with xBic-C-MO2-scrambled (1 pM), xBic-C-MO1 (1 pM and 2 pM), xBic-C-MO2 (1 pM and 2 pM), and xBic-C-MO1 + 2 (1 pM each morpholino oligomer). Image published in: Tran U et al. (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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