Fig. 4. Expression analysis of pronephric markers. (A–H′) Whole mount in situ hybridization analysis of uninjected control and xBic-C-MO1 + 2-injected embryos at stage 38. (A, A′) Nephrin; (B, B′) xSGLT-1K; (C, C′) NKCC2; (D, D′) xNBC1; (E, E′) CAII; (F, F′) ClC-K; (G, G′) NCC; (H, H′) ROMK. (I) Schematic diagram of the pronephric marker genes used. Arrows point to the late distal pronephric tubule, arrowheads indicate the pronephric duct. Image published in: Tran U et al. (2007) Copyright © 2007. Image reproduced with permission of the Publisher, Elsevier B. V.Gene Synonyms Species Stage(s) Tissue nphs1.S nephrin X. laevis Throughout NF stage 37 and 38 glomus slc5a1.2.S D22S675, sglt-1, sglt-1k, sglt1 X. laevis Throughout NF stage 37 and 38 pronephric kidney early proximal tubule late proximal tubule slc12a1.L Na-K-2Cl cotransporter, NKCC-2, NKCC2, XNKCC2 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric tubule early distal tubule slc4a4.L hhNMC, hnbc1, nbc1, nbc2, nbce1, pNBC, slc4a5, XNBC1 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric tubule early proximal tubule late distal tubule ca2.L CA-2, caII, car2, carbonic anhydrase II, carbonic anhydrase type 2 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric tubule early proximal tubule late distal tubule ciliated epidermal cell clcnkb.L ClC-k, clc-kb, clckb, clcnka, clk-k2, xClC-k X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric duct pronephric tubule early distal tubule late distal tubule slc12a3.L ncc, ncct, tsc X. laevis Throughout NF stage 37 and 38 pronephric duct late distal tubule kcnj1.L kir1.1, MGC68935, ROMK, romk1 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric duct pronephric tubule early distal tubule late distal tubule
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