Xenbase Image ID: 79185

Fig. 4. Overexpression of Xror2 and its mutant constructs causes a shortened anteroposterior axis. Two blastomeres of four-cell stage embryos were injected in the ventral (/V) or dorsal (/D) equatorial region with mRNAs (1 ng/embryo) as indicated (A-G). Injected embryos were cultured until stage 38. (A,C) Globin mRNA-injected control embryos. (B) Ventral overexpression of Xror2 causes malformation in posterior structures. (D-F) Dorsal overexpression of Xror2 and kinase domain mutants (Xror2-3I, Xror2-TM) causes a shortened body axis with dorsal bending and abnormalities in head structures, including one-eyed phenotypes. (G) Xror2-KR shows much weaker phenotypes than the other constructs of Xror2. Image published in: Hikasa H et al. (2002) Copyright © 2002. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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