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XB-IMG-79347

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Fig. 5. (A–L) Schematic coronal illustration of neurogenic zones (gray bands surrounding ventricles on left of sections; identified by the distribution of BrDU and pH3 immunoreactivity) and thyroid hormone receptor β (TRβ) immunoreactivity (-ir; large and small dots on right of sections) distribution in the brain of NF stage 52 X. laevis tadpoles following 48 h treatment with T3 (50 nM). TRα mRNA, which is not shown in the figure, is highly expressed in all neurogenic zones and many other areas throughout the tadpole brain. The drawing at the top of the figure shows a dorsal view of the X. laevis brain. Letters correspond to the rostrocaudal location of sections as depicted in the whole-brain drawing. Large circles represent large cells that exhibited robust TRβ-ir, and small circles represent smaller TRβ-ir cells. The anatomical drawings are from Tuinhof et al. (1998), with modifications of basal ganglia subdivisions according to (Marín et al., 1998). Abbreviations are defined in Table 2.

Image published in: Denver RJ et al. (2009)

Copyright © 2009. Image reproduced with permission of the Publisher, Elsevier B. V.

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