Xenbase Image ID: 79515

Fig. 8. The Xenopus Tbx20 334 bp cardiac regulatory element drives EGFP expression in a cardiac-specific manner in zebrafish. (A,B) In situ hybridization depicts expression of Tbx20 in wild-type zebrafish embryos and alk8sk42 (Marques and Yelon, 2009) mutant siblings at the 10-somite stage; dorsal views, anterior to the top. Tbx20 expression is reduced in both the anterior lateral plate mesoderm, including the bilateral cardiac primordia, and the midline mesenchyme of zygotic alk8 mutants. (C-E) Lateral views of a live zebrafish embryo at 48 hpf, following injection with the XTbx20(34)-EGFP transgene. Injected embryos express EGFP in the myocardium (arrows). Image published in: Mandel EM et al. (2010) Copyright © 2010. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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