Xenbase Image ID: 80160

Figure 6. Xenopus golph2 is required for pronephros development. A. Schematic diagram of the pronephros with a summary of the pronephric marker genes that were used (lateral view, anterior towards the left). At stage 38, the pronephros is subdivided into distinct segments: the glomus, proximal tubule (PT1, PT2, PT3), intermediate tubule (IT1, IT2), distal tubule (DT1, DT2) and pronephric duct (PD). B Expression of the marker genes; the orientations of panels B to M show a lateral view, the anterior towards the right; the orientations of panels Bto Mshow a lateral view, the anterior towards the left. A total of 32 ng of Control or golph2 morpholino was injected into a single ventral blastomere of 4-cell-stage embryos from the lateral region; whole-mount in situ hybridization analysis was performed on stage 38. (B Nephrin; (a) transverse section of the embryos in panels Band C (D atp1b1; (F SGLT-1K; (H ClC-K; (J NKCC2; (L NBC1. Image published in: Li L et al. (2012) Li et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue nphs1.S nephrin X. laevis Throughout NF stage 37 and 38 pronephric kidney glomus slc5a1.2.S D22S675, sglt-1, sglt-1k, sglt1 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric tubule early proximal tubule late proximal tubule slc12a1.L Na-K-2Cl cotransporter, NKCC-2, NKCC2, XNKCC2 X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric tubule early distal tubule atp1b1.S atp1b1a, Beta1-Na/K-ATPase, Na+-K+-ATPase, β1-NaK-ATPase X. laevis Throughout NF stage 37 and 38 pronephric kidney pronephric tubule pronephric duct early distal tubule late distal tubule early proximal tubule late proximal tubule clcnkb.L ClC-k, clc-kb, clckb, clcnka, clk-k2, xClC-k X. laevis Throughout NF stage 37 and 38 pronephric duct early distal tubule late distal tubule slc4a4.L hhNMC, hnbc1, nbc1, nbc2, nbce1, pNBC, slc4a5, XNBC1 X. laevis Throughout NF stage 37 and 38 pronephric tubule late distal tubule late proximal tubule Image source: Published Larger Image Printer Friendly View

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