Xenbase Image ID: 80187

Figure 10. Zfp36 depletion does not affect somitogenesis nor early pronephros specification. (A) 20 ng of zfp36 morpholinos (MO) were injected into one dorsal blastomere of 4-cell stage embryos with 250 pg of lacZ mRNA. Embryos were fixed at stage 15 for the detection of myod by in situ hybridization (a) or at stage 28 for immunohistochemistry with 12/101 antibody (d). a, b and c are representative phenotypes and f and g are close up views of d and e respectively. Arrowheads indicate regularly segmented somites on the injected side. (B) 20 ng of zfp36 morpholinos (MO) were injected into one ventral blastomere of 8-cell stage embryos with 250 pg of lacZ mRNA. Embryos were fixed at stage 29/30 (a, b, e, f), 33/34 (c, d) or 27 (g, h) and analysed for the expression of lim1, pax8, wnt4 and wt1 by in situ hybridization. Image published in: Tréguer K et al. (2013) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 15 paraxial mesoderm lhx1.L lim-1, Lim1, lim1, Xlim-1, Xlim1 X. laevis Throughout NF stage 29 and 30 pronephric duct pronephric kidney neural tube pax8.L pax-8, XPax-8, XPax8 X. laevis Throughout NF stage 33 and 34 pronephric kidney wnt4.L wnt-4, Xwnt-4, Xwnt4 X. laevis Throughout NF stage 29 and 30 midbrain pronephric mesenchyme hyoid arch branchial arch trigeminal ganglion spinal cord wt1.S wt-1, wt1-a, wt1-b, Xwt-1, xwt1 X. laevis Throughout NF stage 27 pronephric mesenchyme Image source: Published Larger Image Printer Friendly View

Return to previous page