XB-IMG-80799
Xenbase Image ID: 80799
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Figure S1. Comparative Expression of Admp and Chordin during Early Xenopus Development. (A and A' Chordin expression is first detected in superficial cells at the blastula stage in a dorso-animal domain (which spans animal cap and marginal zone cells) corresponding to the BCNE (Blastula Chordin and Noggin Expressing) Center (Kuroda et al., 2004). The BCNE center gives rise to brain, floor plate and notochord at later stages of development. The dotted line indicates the direction of the section shown in the right panel. (B and B Admp expression is detected at stage 9 in a similar dorso-animal domain, but in cells located deeper than the ones expressing Chordin. (C and C At stage 11, expression of Chordin expands and is seen in involuted cells of the future prechordal plate (pp) and midline. (D and D At a similar stage, Admp is also expressed locally in involuting cells of the prospective midline, but in a narrower and more posterior domain than that of Chordin. (E and E At stage 13, Chordin is expressed in a broad domain within the prechordal plate (pp) and in notochord (no). (F and F Admp expression at stage 13 is localized to the floor plate (fp), a superficial layer of midline cells overlying the notochord. (G and G Expression of Chordin at early neurula stage persists in the notochord (no) and is turned off in the prechordal plate. (H and H At early neurula stage, Admp expression fades and is seen only in the posterior-most region of the floor plate. (I and J) At tadpole stage, Chordin expression is restricted to the posterior notochord, while expression of Admp is no longer detectable. Image published in: Reversade B and De Robertis EM (2005) Copyright © 2005. Image reproduced with permission of the Publisher, Elsevier B. V.
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