Xenbase Image ID: 80834

FIG. 4. Heart morphology in embryos treated with retinoic acid. The heart morphology of control embryos at stage 38 is seen in (A), with an enlarged view of a control heart in (D). At the equivalent stage, embryos that were treated with 10 I-'M RA at stage 10.5 (B) have hearts which are extremely reduced in size or absent (bottom embryo). An enlarged view (E) shows the significant reduction in heart size in RA-treated embryos. Note that many other anterior structures are also absent. (C) Embryos at the equivalent of stage 38 that were treated with 10uM RA at stage 15. These show almost normal morphology of anterior structures but the hearts are smaller than those in control embryos. The enlarged view (F) shows a failure of the heart to separate into distinct chambers. In all RA treatments, the heart tissue migrated to the ventral midline. Image published in: Drysdale TA et al. (1994) Copyright © 1994. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue tnni3.L c-troponin, cardiac tropin T, cardiac troponin I, cTnI, ctnIc, cTNT, TIc, TnIc, tnnic, troponin-ic, XcTnI, XTnIc X. laevis Throughout NF stage 37 and 38 heart Image source: Published Larger Image Printer Friendly View

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