Xenbase Image ID: 80997

Fig. 2. Tcf21 is required for epicardial integrity and adhesion to the myocardial surface. (A-P) SEM images of hearts from control and Tcf21-depleted Xenopus embryos (A,C,E,G,I,K,M,O) with magnified views of the ventricular region (B,D,F,H,J,L,N,P). Blue dashed line indicates the extent of epicardial sheet migration over the ventricular surface. Ventral views of pericardial cavity with anterior at top (A-P). (Q-T′) Toluidine Blue staining (Q,R) (dorsal at top) and TEM images (S-T′) of transverse sections through the heart region demonstrating adhesions, or lack thereof, to the underlying myocardial surface (red arrows). The boxed regions in Q,R are magnified in S-T′. a, atrium; en, endocardium; ep, epicardium; m, myocardium; oft, outflow tract; peo, proepicardial organ; v/ven, ventricle. Scale bars: 50 μm in A,C,E,G,I,K,M,O; 25 μm in B,D,F,H,J,L,N,P; 5 μm in S,T; 2 μm in S′,T′. Image published in: Tandon P et al. (2013) Copyright © 2013. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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