Xenbase Image ID: 81463

Figure S10. Cell proliferation and apoptosis in xSuv4-20h double morphants. (A) Double morphants show increased number of apoptotic cells during neurulation. Top row immunocytochemistry for active Caspase3 in unilaterally injected embryos (NF15). Middle and bottom rows - RNA in situ hybridisation for Delta-like 1 (NF13) and N-tubulin mRNAs (NF15). Pictures show dorsal views, with anterior to the left. (B) Proliferation assay immunocytochemistry for the mitotic histone modification H3S10P in Crtl-MO versus double morphant embryos. The chart shows a two-fold difference in the number of H3S10P positive cells on the injected side of double morphants. Data represent mean values of four embryos per condition from two independent experiments; error bars indicate SEM. Image published in: Nicetto D et al. (2013) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue dll1.L delta-1, Delta-1, delta1, x-delta, X-delta-1, Xdelta-1, Xdelta1, XDelta1 X. laevis Throughout NF stage 13 neuroectoderm neural plate circumblastoporal collar neural progenitor cell neural plate border tubb2b.L N-Tub, n-tubulin, NBT, neural beta-tubulin, NST, ntubulin, Xn-tubulin X. laevis Throughout NF stage 15 neuroectoderm neural plate interneuron neural progenitor cell sensorial layer Image source: Published Larger Image Printer Friendly View

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