Xenbase Image ID: 81922

Fig. 3. Expression patterns of shortlisted targets. In situ hybridisation analysis of Esr1, Esr2, FoxC1, mesogenin (MSGN1), Myf5, SEB4 and Tbx6 expression patterns at gastrula, neurula and tailbud stages. All the putative target genes are expressed circumblastoporally at gastrula stages. After gastrula stages, many of the targets are still expressed in the posterior mesoderm in the tailbud region of the embryo, which is the source of myogenic progenitors at this stage. On the right, a temporal expression profile, based on microarray data, is shown for each putative target genes depicting relative expression levels from NF stage 8 to stage 15. The expression of MyoD is shown in the three bottom panels for comparison. Image published in: Maguire RJ et al. (2012) Copyright © 2012. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue hes5.L esr-1, esr1, hes5.1, XESR-1 X. laevis Throughout NF stage 11 mesoderm lateral plate mesoderm chordal neural plate hes5.L esr-1, esr1, hes5.1, XESR-1 X. laevis Throughout NF stage 18 mesoderm chordal neural plate Rohon-Beard neuron presomitic mesoderm trigeminal placode hes5.L esr-1, esr1, hes5.1, XESR-1 X. laevis Throughout NF stage 28 brain forebrain midbrain hindbrain chordoneural hinge eye retina trigeminal ganglion otic vesicle lateral line placode spinal cord hes5.3.L esr-2, esr2, hes3.3 X. laevis Throughout NF stage 11 mesoderm involuting marginal zone vegetal part, early involuting hes5.3.L esr-2, esr2, hes3.3 X. laevis Throughout NF stage 18 mesoderm presomitic mesoderm tail region hes5.3.L esr-2, esr2, hes3.3 X. laevis Throughout NF stage 28 brain forebrain midbrain hindbrain eye retina trigeminal ganglion lateral line placode chordoneural hinge spinal cord foxc1.S fkhl7, foxc1-a, foxc1-b, freac-3, freac3, igda, ihg1, irid1, rieg3, xfd-11 X. laevis Throughout NF stage 10 mesoderm involuting marginal zone vegetal part, early involuting involuted ventral mesoderm ventro-lateral marginal zone foxc1.S fkhl7, foxc1-a, foxc1-b, freac-3, freac3, igda, ihg1, irid1, rieg3, xfd-11 X. laevis Throughout NF stage 18 mesoderm lateral plate mesoderm presumptive paraxial mesoderm foxc1.S fkhl7, foxc1-a, foxc1-b, freac-3, freac3, igda, ihg1, irid1, rieg3, xfd-11 X. laevis Throughout NF stage 28 pronephric mesenchyme prechordal plate head mesoderm chordoneural hinge tail region periocular region msgn1.L mes1, mesogenin, MesP-related bHLH factor, Mespo, msgn1-a, msgn1-b, pMesogenin1 X. laevis Throughout NF stage 10 mesoderm involuting marginal zone involuted ventral mesoderm ventro-lateral marginal zone msgn1.L mes1, mesogenin, MesP-related bHLH factor, Mespo, msgn1-a, msgn1-b, pMesogenin1 X. laevis Throughout NF stage 18 mesoderm presomitic mesoderm paraxial mesoderm msgn1.L mes1, mesogenin, MesP-related bHLH factor, Mespo, msgn1-a, msgn1-b, pMesogenin1 X. laevis Throughout NF stage 28 chordoneural hinge tail region tail bud mesoderm myf5.L myf-5, Xmyf-5, Xmyf5 X. laevis Throughout NF stage 11 involuting marginal zone dorso-lateral marginal zone myf5.L myf-5, Xmyf-5, Xmyf5 X. laevis Throughout NF stage 18 presomitic mesoderm presumptive paraxial mesoderm myf5.L myf-5, Xmyf-5, Xmyf5 X. laevis Throughout NF stage 28 presomitic mesoderm chordoneural hinge somite spinal cord tail region rbm24.L rbm24-a, rbm24-b, seb-4, seb4, seb4-a, SEB4-LIKE, xseb4 X. laevis Throughout NF stage 10 involuting marginal zone dorso-lateral marginal zone ventro-lateral marginal zone ventral marginal zone rbm24.L rbm24-a, rbm24-b, seb-4, seb4, seb4-a, SEB4-LIKE, xseb4 X. laevis Throughout NF stage 18 presomitic mesoderm paraxial mesoderm rbm24.L rbm24-a, rbm24-b, seb-4, seb4, seb4-a, SEB4-LIKE, xseb4 X. laevis Throughout NF stage 28 presomitic mesoderm paraxial mesoderm intersomitic region tbx6.L XTbx6 X. laevis Sometime during NF stage 10 to NF stage 10.25 involuting marginal zone ventro-lateral marginal zone tbx6.L XTbx6 X. laevis Throughout NF stage 18 mesoderm presumptive paraxial mesoderm tbx6.L XTbx6 X. laevis Throughout NF stage 28 presomitic mesoderm somite eye otic vesicle branchial arch tail bud myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 11 mesoderm involuting marginal zone ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 18 presomitic mesoderm paraxial mesoderm myod1.S mf25, MyoD, myod1-a, myod1-b, myogenic factor 3, XMyoD, XtmyoD X. laevis Throughout NF stage 28 presomitic mesoderm somite myotome Image source: Published Larger Image Printer Friendly View

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