XB-IMG-82169
Xenbase Image ID: 82169
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Fig. 1. Xmab21l3, a novel Mab-21 family protein, is a target of Xema, (A) Xema misexpression upregulates Tx1 in animal caps. RT-PCR analysis of Tx1 expression in animal caps derived from Xema RNA-injected embryos. 25 cycles of PCR were used for detection of Tx1. (B) Xema knockdown induces mesoderm and inhibits expression of Tx1. 33 cycles of PCR were used for detection of Tx1. (C) Tx1/Xmab21l3 encodes a Mab-21 family protein domain (Xmab21l3 aa 5856). (D) The Mab21l3 proteins are more similar to each other than to other Mab-21 family proteins. Dendrogram highlighting the percentage similarity between Xmab21l3 and other Mab-21 family proteins in H. sapiens, M. musculus, X. laevis, D. melanogaster, C. elegans. The dendrogram was generated using ClustalW (http://www.genome.jp/tools/clustalw/) and visualized by NJpolt software (http://pbil.univ-lyon1.fr/software/njplot.html). Branch lengths are proportional to distance. Numbers indicate GI.
Image published in: Sridharan J et al. (2012) Copyright © 2012. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |