Xenbase Image ID: 82316

Figure2. Spindle Position Does Not Correspond to Cell-Cell Junction Location(A) Immunofluorescence for ZO-1 (green), a component of tight junctions, shows that spindle position does not correlate with the location of tight junctions.(B) -Catenin (green), a component of adherens junctions, is localized all around the basolateral cell surfaces.(C) Transmission electron micrographs (zoomed-in areas highlighted in red, yellow, and blue boxes) show that tight junctions (TJ) and the zona adherens (ZA) are located apically and stretch no more than 2.5m down from the apical cell membrane (red box), whereas regions of high density, which may be cell-cell contacts (yellow and blue boxes; arrows), are found at random positions around the basolateral membranes.Scale bars represent 10m in (A) and (B) and are as displayed in (C). Image published in: Woolner S and Papalopulu N (2012) © 2012 ELL & Excerpta Medica. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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