Xenbase Image ID: 82477

Figure 2. Ventral expression of Xhairy2b induces a secondary axis and inhibits ventralizing factors. A,B: Uninjected control embryo and Xhairy2b mRNA ventrally injected embryo, respectively, at stage 35. Xhairy2b mRNA ventral injection results in the induction of secondary axes lacking head structures (arrowhead). C: Transverse section of the embryo shown in B. Secondary axis (arrowhead) has neural tube and somitic mesoderm but lacks notochord. no, notochord, nt, neural tube, so, somite. D,D′′: Uninjected control embryos (D) and Xhairy2b mRNA (800 pg) ventrally injected embryos (D′′) are shown in vegetal view, dorsal side up at stage 10.5. D′′: Expression of organizer genes, follistatin (D′), frzb1 (E′), and admp (F′) is ectopically induced by Xhairy2b (arrowheads). G′: The expression of Xvent1 and Xvent2 in the ventral region (G,H) is reduced by Xhairy2b expression (G′,H′, arrowheads). Image published in: Yamaguti M et al. (2005) Copyright © 2005. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue fst.L foll, follistatin, xfs X. laevis Throughout NF stage 10.5 involuted dorsal mesoderm involuting marginal zone frzb.S fiz, fre, frp-3, Frzb-1, frzb-pen, frzb1, fzrb, os1, sfrp3, srfp3, xfrzb X. laevis Throughout NF stage 10.5 upper blastopore lip admp.S X. laevis Throughout NF stage 10.5 involuted dorsal mesoderm ventx1.2.S vent-1, vent1, Xvent-1, Xvent1 X. laevis Throughout NF stage 10.5 involuted ventral mesoderm marginal zone ventral marginal zone ventx2.2.L vent-2, vent2, Xom, xvent-2, xvent2 X. laevis Throughout NF stage 10.5 marginal zone ventral marginal zone ventro-lateral marginal zone dorso-lateral marginal zone Image source: Published Larger Image Printer Friendly View

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