Xenbase Image ID: 82744

Fig. 5. Phenotype of xBtg-x antisense morpholino oligomer injections. (A) In vitro transcription/translation of pCS2-xBtg-x in the presence of control morpholino and xBtg-x-MO1. (B) Histological analysis of uninjected control embryos and (C) embryos injected at the 2-cell stage with xBtg-x-MO1 + 2 at stage 40; en, endoderm; nt, neural tube; no, notochord; so, somites. (D�K) Whole-mount in situ hybridization of uninjected and xBtg-x-MO1 + 2 injected embryos at neurula stage 14. (D, E) Combination of Otx2, Krox20, and HoxB9 probes; (F, G) Sox-2; (H, I) Pax3; (J, K) Slug. Note that xBtg-x-MO1 + 2 inhibits neural plate convergence and extension movements. Image published in: Wessely O et al. (2005) Copyright © 2005. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue otx2.S otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 18 pre-chordal neural plate egr2.L EGR-2, Krox-20, krox20, XKr20, XKrox-20 X. laevis Throughout NF stage 18 rhombomere R3 rhombomere R5 anterior branchial crest hoxc9-like.L X. laevis Throughout NF stage 18 trunk region chordal neural plate sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 18 neural plate neuroectoderm pax3.S cdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3 X. laevis Throughout NF stage 18 neural plate neural crest snai2.L slug, snai2-a, snai2-b, Snail2, xSlu, xslug, XSnail2 X. laevis Throughout NF stage 18 neural crest cranial neural crest Image source: Published Larger Image Printer Friendly View

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