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Fig. 5. Inhibition of organizer-specific gene expression by BMP signaling as a function of time. Embryos were injected with Smad1/GR mRNA and treated with dex at the specified stages. Four hours after the dex treatment was initiated, the embryos were fixed and processed for in situ hybridization with gsc (A�F), Otx2 (G�L), and Xnot2 (M�R) specific probes. The numbers summarize the percentage of embryos resembling the representative embryo and the sample size.

Image published in: Marom K et al. (2005)

Copyright © 2005. Image reproduced with permission of the Publisher, Elsevier B. V.

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