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Figure 4. The mlo Mutation Exhibits Paralysis and Motor Neuron Defects Neural tissue of mlo and diploid control was stained with the HNK-1 antibody. In wild-type tadpoles ([A] and [C]), motor neuron axons (white arrow) travel down the intermyotomal cleft from the neural tube; in mlo ([B] and [D]) the axonal tracts (black arrow) wander away from the intermyotomal space. In situ hybridization with cardiac actin ([E] and [F]) shows that somite structure is relatively unaffected. doi:10.1371/journal.pgen.0020091.g004 Image published in: Goda T et al. (2006) Copyright: © 2006 Goda et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue b3gat1l.L cd57, glcatp, glcuatp, hnk-1, hnk1, leu7, nk-1, nk1 X. laevis Throughout NF stage 37 and 38 brain spinal cord central nervous system motor neuron motor axon actc1.L actc, actna1, cardiac actin, cardiac alpha actin, muscle actin X. laevis Throughout NF stage 37 and 38 muscle skeletal muscle hypaxial muscle epaxial muscle Image source: Published Larger Image Printer Friendly View

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