Xenbase Image ID: 82952

Figure 5. wha Embryos Show Defects in Hematopoeisis Whole mount in situ hybridization with α-globin suggests that wha blood distribution is aberrant ([A] and [C]), with reduced globin staining pooled ventrally (black arrows) rather than distributed throughout the circulatory system as in wild-type tadpoles. Comparison of ventral views of wha (C) globin staining with that of muzak (B), a mutant which is impaired in heart function but not hematopoiesis, leading to ventral pooling of normal levels of blood (white arrows), confirms that wha is quantitatively defective in blood formation rather than circulation. See also Tables 6 and 7 for microarray analysis of wha. doi:10.1371/journal.pgen.0020091.g005 Image published in: Goda T et al. (2006) Copyright: © 2006 Goda et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Gene Synonyms Species Stage(s) Tissue hba4.S alphaT4-globin, aT4 Globin, T4 globin X. laevis Throughout NF stage 37 and 38 blood Image source: Published Larger Image Printer Friendly View

Return to previous page