Xenbase Image ID: 83631

Figure 5. Temporal expression patterns of already-known genes that are related to blood vessel differentiation in Xenopus. Dashed arrows indicate the temporal expression of each gene in prospective and forming regions of the blood vessel, as follows: DLP, dorsal lateral plate; AA, aortic arches; PCV, posterior cardinal vein; ISV, intersomitic vein. The differentiation processes of blood vessel formation are indicated in the middle. The timing of definitive differentiation of the hemangioblast is not well understood, but it is known that the hemangioblasts located in the DLP differentiate into adult blood cells and vascular endothelial cells. Fli1 is known to be a marker of hemangioblasts (Liu et al.,2008). The start of vasculogenesis and angiogenesis is clearly observed as the expression of Xmsr in the AA or PCV and the expression of Xtie2 in the sprouting ISV, as determined by whole-mount in situ hybridization. We identify two novel potential marker genes, Ami and XRASGRP2, for the late differentiation of blood vessels, angiogenesis and/or maturation.Download figure to PowerPoint Image published in: Asashima M et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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