Xenbase Image ID: 83633

Figure 7. Schematic representation of pronephros development in X. laevis. The expression of molecular signals is accompanied by the differentiation of the tubule, duct, and glomus. The expression of Lim-1 and Pax-8 in the pronephric mesoderm determines the analgen of pronephros at stage 12.5. At stage 20, the anlagen of the pronephros thickens and becomes morphologically discernible, and the expression of Pax-2, Wnt-4, WT1, and other molecules begins at pronephros. By stage 25, the genes involved in the patterning and morphogenesis of the pronephros are activated. The pronephros is separated from the lateral plate, and further differentiation commences at the late tail-bud stage. The genes shown in blue, green, and red letters represent genes that are involved in the development of the tubule, duct, and glomus.Download figure to PowerPoint Image published in: Asashima M et al. (2009) Copyright © 2009. Image reproduced with permission of the Publisher, John Wiley & Sons. Larger Image Printer Friendly View

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