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Figure S4. Signaling centers in the central nervous system show elongated monocilia. Scanning electron microscopy pictures of sagittally bisected brain explants at stage 45. (A) The isthmus organizer (mid-hindbrain boundary) region; note the presence of several elongated monocilia on the mesencephalic aqueduct side (outlined arrowheads) as well as a population of monociliated cells on the ventral (v) aspect of the isthmus (arrowheads). (B) Close-up view onto the lumen of the spinal cord. Arrowheads point to elongated monocilia projecting into the central canal, the appearance of which correlates with expression of foxj1 (cf Figure 1B-F, Figure 2A). a = anterior; d = dorsal;
p = posterior. Image published in: Hagenlocher C et al. (2013) Copyright © 2013 Hagenlocher et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View |